Theoretical basis of diabetestreatmentin the framework ofthe new conception relating to the closed 9-stepped cycle of proton conductance

Closed 9-stepped cycle,proposedby M.Ambaga means that after completing all 9 stages, the system returns to its original state. The movement of protons is cyclic, with no net loss or gain of protons in the overall system, just a continuous movement within the defined cycle. The cycle being closed ensures that the process is efficient and self-sustaining, as it doesn't require new inputs from outside once the cycle is running. In biological systems, such cycles are important for energy conservation and regulation of processes like ATP synthesis. During Diabetes have beendisturbed the above mentioned Normal thermodynamic processes, conducted in the Closed 9-stepped cycle of proton conductance as exergonic reactions are favorable, or spontaneous reactions, no needed new inputs from outside, self-sustaining, after completing all 9 stages, the system returns to its original state. It can be say that according to the Closed 9-stepped cycle of proton conductance, the molecular mechanism of diabetes have been characterized by pathological increase of glucose in the second compartmernt – extacellular -blood serum location (hyperglycemia) of Human body and pathological decrease of glucose in the first compartment of Human body , because of in this case have been occurred the decrease of entry of glucose to metabolic medium as “Donators of proton as glucose molecules (first stage of proton conductance) + membrane redox potentials in the three-state line system + O2 (hemoglobin of the pulmonary capillary -8-th stage, hemoglobin of tissue-87 trillion cell-surrounded capillary-9-th stage) + ADP + Pi + (H+ + nH + memb.space - proton gradient-4-th stage) = (ATP + heat energy-5-th stage) + H2O (5-th stage) + (nH + matrix) + CO2(second stage of proton conductance).