Plants play an important role on medicines since thousands of years to treat various diseases. Oxidative stress may precede and speed up to development of diabetes. In diabetic complications antioxidant action may be an important property of medicinal plant linked with diabetes. The Lily family, Liliaceae, consists of fifteen genera about 600 species of flowering plants with in the order. Onion (Allium cepa) belongs to the Lilly family, it shows only a particular vertical shoot above the ground and is used for energy storage and as a spice. It could be in a range of shapes and sizes. Garlic (Allium Sativum) also of the lilly family has a strong characteristic odour and taste and the bulb is used a flavoring agent. Both plants of medicinal values excluding common cold, heat disease, osteoporosis and other diseases, which may be associated with its high bioactive compounds including flavonoids, polyphenolic and antioxidant properties. In the present study antioxidant activity of Liliaceae family was assayed by DPPH scavenging activity, flavonoid and total polyphenolic content.