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Treatment outcome of Tuberculous lymphadenitis

Author: 
Dr. Deepali R Gaikwad
Subject Area: 
Health Sciences
Abstract: 

Objective: To evaluate treatment outcome of tuberculous (TB) lymphadenitis at Bhausaheb Sardesai Talegaon Rural Hospital (BSTRH), Attached with M.I.M.E.R. Medical college, Talegaon Dabhade, Maharashtra. Results: Of total 757 tuberculosis cases and 202 extrapulmonary amongst them, 70 (9.24%) patients had TB lymphadenitis.The mean age was 28.8±12years. Commonly affected site observed cervical group 40 (57.1%) with single node involvement seen in 54 (77.1%) cases. Sputum AFB positive in 1 patient (1.4%), HIV association seen in 3 (4.3%) cases. Fever and anorexia were most frequently reported sympoms. Fine needle aspiration showed positive results in majority of cases 61 ( n=70, 87.1%). One (1.4%) patient diagnosed multiple drug resistance. Paradoxical reaction was observed in 5 (7.2%) patients. All patients were treated with Directly Observed Therapy. Fifty nine (84.3%) patients were treated successfully, 4 (5.7%) patients required extension of treatment. five (7.2%) patients exhibited paradoxical reaction, one (1.4%) patient showed relapse. One( 1.4%) patient diagnosed multiple drug resistance and required 2nd line of antitubercular treatment. Conclusion: Lymphnode is commonly affected organ by tuberculosis (9.24%). Lymphnode tuberculosis is most common form of extrapulmonary tuberculosis (34.6%). Incidence was slightly higher in female than male gender. FNA is most reliable diagnostic test. TB lymphadenitis cases showing paradoxical reaction and or relapse should be subjected for drug susceptibility testing to rule out drug resistant tuberculosis.

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