Background: For pre-surgical assessment of an adnexal mass, the International Ovarian Tumor Analysis (IOTA) ADNEX model can be used by medical doctors to diagnose ovarian cancer in women who have at least one persistent adnexal and estimates the probability that an adnexal tumor is benign or malignant. Objective: To study the value of the international ovarian tumor analysis (IOTA) in differentiation between malignant and benign ovarian tumor. Patients and methods: Fifty one patients presented with suspicious adnexal mass to the radiological department in Baghdad teaching hospital in medical city complex in the period from February 2016 till the end of December 2016. U/S was performed to confirm & characterize the adnexal mass. CA-125 tumor marker was measured. All patients underwent surgery to remove the mass and the masses were sent for histopathological study. Results: the IOTA score was calculated and compared, and shows that IOTA score was efficient in the determination of benign or malignant. The sensitivity of the IOTA score system was 92% and specificity was 98% in detection the malignant at cut off point 49.25%. Conclusion: the IOTA score (ADNEX model) was highly sensitive (92%) and highly specific (98%) in detection of benign or malignant at score of 49.25.
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