An unusual case report of two Collodion babies on successive deliveries of a mother

Background: Collodion Baby refers to clinical presentation in neonates present within a thick taut shiny translucent membrane resembling a collodion, usually this membrane sheds off within 2-3 weeks after birth Case Characteristics: Both the infants were full term and had abnormal skin with ectropion and eclabium. Apgar was normal with no gross systemic anomalies. Intervention: The infants were placed in an incubator and temperature monitoring, IV antibiotics, fluid and electrolyte replacement was done. Outcome: Both the infants died 1 in hospital due to sepsis and second one during transportation so we cannot ascertain the etiology. Message: Early diagnosis and intervention can reduce morbidity and mortality in neonates.