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In vitro Cytotoxicity, Phytochemistry and GC-MS analysis of Averrhoa carambola (leaf) against MCF-7 breast cancer cell line

Author:

Poongodi, T and Dr. Nazeema, T. H.

Subject Area:

Life Sciences

Abstract:

The current investigation was carried out to study the preliminary phytochemical screening, GC-MS and In vitro cytotoxicity assay of leaf extract of Averrhoa carambola. Phytochemical screening revealed the presence of active plant metabolites like alkaloids, glycosides, phenol, tannins, flavonoids, protein and diterpenes. It was further continued to identify 10 different compounds of medicinal use in the Averrhoa carambola by GC-MS analysis. The study also investigated about the Invitro cytotoxic nature of Averrhoa carambola leaves in breast cancer cell line (MCF-7) using MTT assay. IC50 value was found to be 170.326 µg/ml.

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