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In vitro screening of anti-inflammatory potential of mirabilis jalapa linn flowers and abelmoschus esculentus leaves

Author: 
Sunmathy Kanakamani, Saraswathi Uthamaramasamy and Malathi Mangalanathan
Subject Area: 
Social Sciences and Humanities
Abstract: 

Background: Flowers of Mirabilis jalapa were used as traditional medicine in Asia, Europe, America and Africa as purgative, diuretic and wound healing. Abelmoschus esculentus (Leaves) were used to treat abdominal pain, diarrhoea, genitourinary and respiratory problems. Objectives: The present study was to evaluate the anti-inflammatory potential of 50% hydro ethanol extracts of Mirabilis jalapa flowers and leaves of Abelmoschus esculentus through various in vitro assays. Methods: The anti-inflammatory activity was demonstrated by inhibiting the heat induced albumin denaturation, membrane stabilization and protein denaturation activity. Results: The results of the study revealed that Mirabilis jalapa flower extract exhibited increased anti-inflammatory activity at the concentration of 0.1g/ml than the leaves of Abelmoschus esculentus which is comparable to that of the standard Aspirin. Conclusions: From the results, it is concluded that Mirabilis jalapa flowers were a source of high-value health promoting commodity which can be administered for its anti-inflammatory activity.

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