Dysfunction of liver and kidney in diabetes mellitus an observational study

Introduction: Liver disorder is known to be a risk factor for diabetes and diabetic patients are at risk of developing liver disorders. Association of liver and renal disease is less explored in the field of research. Aim: To estimate prevalence of abnormal Liver function in diabetes, and to study prevalence of nephropathy in diabetes categorized as: at <5yrs; 5-10 yrs; >10 yrs. Materials and Methods: The study and observation was done in sample of 300 subject of type II Diabetes mellitus from March 2012 to Aug 2013. Based on duration of Diabetes mellitus, subject were distributed according to <5yrs, 5-10yrs and >10yrs of illness. Out of 300 type II Diabetes mellitus subject 75% were male and female group was 25%. Results: With reference to liver function test 21% patient were having abnormal liver function test. The prevalence of diabetes nephropathy i.e. 35% overall. Prevalence of nephropathy increased with increasing duration of Diabetes mellitus. Conclusion: In the study Liver enzyme was elevated overall 21 % more than 3 times, 0.66% were detected with HCV reactive, fatty liver disease was most common finding, Macroalbuminuria present in 7.3 % of subject.