Thrombocytopenia in pregnancy: a hospital based study

Background: Thrombocytopenia is seen in 6 to 10% of pregnant women, with the gestational thrombocytopenia being the most important etiological factor. Objective: To study the maternal and perinatal outcome of thrombocytopenia in pregnancy. Materials and Methods: In this study, 110 pregnant women, irrespective of their gestational ages were studied in the Department of Obstetrics and Gynaecology, SKIMS, Srinagar over a period of one year from April 2017 to March 2018. Proper history was taken and detailed examination done in all patients. All the women were followed throughout the pregnancy till delivery. Maternal and fetal outcomes were noted. Results: Out of 110 patients, 95 (86.37%) had moderate thrombocytopenia and 15(13.63%) had severe thrombocytopenia. In this study, 40% cases were primigravidas, 31% were gravida 2 and 29% were more than or equal to gravida 3. The most common etiological factor was gestational thrombocytopenia (37.2%) followed by pregnancy induced thrombocytopenia (27.2%) and intrahepatic cholestasis (24.5%) in addition to other less frequent causes. Mean gestational age at diagnosis was 37.48+2.87. There were 2 maternal deaths (1.8%), 3 still births (2.72%) and 2 neonatal deaths (1.8%). The complications were more frequent in those with severe thrombocytopenia. Conclusion: Proper management and timely adequate administration of blood and blood products have a significant impact on maternal and fetal morbidity and mortality.