The thalassemia syndrome are heterogenous group of disorders of hemoglobin synthesis, with a considerable frequency in middle eastern countries. In this study a total of 56 patients were studied, 32 males (57%) and 24 females (43%), aged between (0.3- 30) years, they were divided into three groups: non transfused, group I- (n=11), transfused non splenectomized, group II- (n=34) and transfused splenectomized, group III- (n=11). In non transfused , group I, 90.9% had severe to moderate anaemia, and in transfused non splenectomized, group II, 88.2% had severe to moderate anemia, while in transfused splenectomized, group III, 72.7% had severe to moderate anaemia, and blood transfusion requirements were reduced in 81.8% after splenectomy.
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