We report here a case of black fly bite on the face of a middle-aged Arab lady. She presented with a fairly large-sized, painful swelling of size 7*5 cm on her left cheek of 3 days duration. She visited a picnic spot on the mountains of Dhofar two days prior to the hospital visit and developed a large abscess on her cheek. Incision and drainage done under local anaesthesia. Black flies infection was rampant in the monsoon season, on the mountains of Dhofar region in Oman. These flies are hematophagous flies and affects cattle, wild animals, birds and humans. Death from mass attack reported in cattle, due to release of toxin from its saliva. It bites humans and causes significant lesions like abscesses on the face and the public be informed about the precautionary measures. Dangerous black fly infection in humans is not ever reported from Oman in the medical literature. We would like to draw attention of the practicing doctors and public about this infectious disease.