Climbing responses of few species of drosophila on exposure to different aniti epileptic drugs

Feeding flies on wheat cream agar media supplemented with antiepileptic drugs are studied for adult locomotary behaviors like preferential adult geotaxis. The behavioral plasticity of climbing ability of an adult is an important event with decisive influence on their preference and capability. Drosophila sensory systems contribute to detect, localize and provide information about the availability of food and chemical features of environments. The present study revealed that the Dose dependent action of different AEDs produced a maximal effect on behaviors of Drosophila species and provides an efficient system to study genetic, neurological, and behavioral mechanisms mediating these effects. Irrespective of the species the responses are similar on exposure to higher doses with decreased activity. AED has an important role in regulating behavior through metabolism; such studies should be useful for understanding the multiple effects on behavior and health.