
Aims: To assess and co-relate the healing efficiency of Modified 3 mix plus Dexamethasone combination paste and metapex in pulpally involved primary molars. Methods and Material: This study comprised of 60 Primary mandibular molars, which were divided randomly into Group A and Group B, Each treated case was recalled for Clinical and radiographic evaluation at one week, one month and six month interval. Group A: All accessible coronal and radicular pulp was removed, followed by medicational cavity preparation and Modified 3 mix plus Dexamethasone placement in meditational cavity and sealed it in single sitting. Group B: Conventional single sitting pulpectomy was performed using metapex as an obturating material. Stainless steel crown cementation was done on the same visit and used as final restoration in both groups. Results: Among 60 molars, Postoperative follow up of clinical examinations at one, and six months was 93.3% and 90% in group A and while in group B was 100%, and 96.7%.so, there was no statistically significant difference in results between Group A and Group B at any follow up, as demonstrated by fisher exact test. (p value=1 at 1 week , p value=0.52 at 1 month and p value=0.35 at 6 months). Conclusions: Modified 3 mix plus Dexamethasone in primary teeth has shown good clinical and radiographic success which is comparable to conventional pulpectomy treatment.