Objective: This study aims to evaluate the outcome of ligasure hemorrhoidectomy versus conventional (Milligan Morgan) hemorrhoidectomy regarding blood loss, lenghth of the procedure, postoperative pain and wound healing. Method: This prospective study was included 40 patients with grade III, or IV hemorrhoid. Patients divided into 2 groups Conventional (Milligan- Morgan) hemorrhoidectomy for 20 patients and Ligasure hemorrhoidectomy for 20 patients. Result: This study defined that the application of Ligasure hemorrhoidectomy was associated with shorter operative time, almost bloodless operative field, smooth postoperative period with lower pain score, analgesic requirement and lower incidence of postoperative complications. In addition, it found that patient satisfaction significantly more superior after Ligasure hemorrhoidectomy. Conclusion: Ligasure hemorrhoidectomy is safe, effective, associated with lower pain and fewer postoperative complications than conventional hemorrhoidectomy.