Six mixed breed dogs aged between seven to eight years were presented to the TVCC, CVSc & AH, CAU, Selesih, Aizawl, Mizoram with the history of anorexia, tenesmus, lethargy, dull and depressed with dribbling of foul smelling bloody urine for few days. Physical examination revealed slightly tensed abdomen with pale mucous membrane. Blood biochemical examination revealed significantly decreased haemoglobin, packed cell volume, total erythrocyte count, total protein and albumin with significantly elevated blood urea nitrogen, serum creatinine and leukocytosis with neutrophilia. Lateral abdominal radiography revealed cranial displacement of urine filled urinary bladder with slightly enlarged prostate which descended from the pelvic cavity. Ultrasonography revealed loss of bi-lobed prostate appearance with presence of three anechoic cavities and parenchyma surrounding the cavity was slightly hypoechoic and heterogeneous which was diagnosed as prostatic cyst. Diffusely enlarged prostate with uniform echotexture, spherical in sagittal section and asymmetrical on transverse plane was diagnosed as prostatic hyperplasia.