Aim: This study was aimed to review the role of die systems in prosthodontics and how it is relevant to fixed prosthodontics. Methodology: A systematic literature search was performed electronically and also hand-searched with terms. The search was carried out through Medline via Pubmed, Wiley online library, Ebscohost, Science Direct, and the Google Scholar for articles published from 2000 to 2019. A total of 172 articles were found. A total of 111 articles were found relevant to the topic. Articles selected were critically appraised to evaluate their quality. Results: Different articles described various die systems its advantages and disadvantages. The literature search revealed 33 articles in PMC. 56 articles were found on Wiley online library, 32 articles in google search, 22 articles in Ebscohost. Additional 29 articles were identified by hand search. Conclusion: An accurate working cast with removable dies is essential to make a well-fitting restoration. Detailed reproduction of die materials for fixed prosthesis affect the accuracy of operating casts and was expounded to the compatibility between the die and impression materials.