Aim: The aim of this study was to determine the Efficiency and Effectiveness of Oral Health Manual designed for care givers of Special children. Methods: Caregivers at Sathya Special School, Pondicherry were selected. A total of 100 caregivers participated in this study out of which 93 participants took the pre-test and 89 took the post test. A 14 multiple choice question bank was designed to evaluate the knowledge amongst the care gives based on the specially designed copyrighted manual prepared with regards to oral hygiene maintenance. Results: The test reveals there was a significant raise for percentage of correct answer before and after with a increase of 10 percentages which was found to be statistically highly significant with P Value .000 Conclusion: It is evident that the knowledge of the caregivers of special children about the oral health practices and their attitude towards oral hygiene maintenance is better