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Faecal calprotectin in patients with colorectal cancer: a hospital based cross sectional study

Author: 
Awhad Mueed Yousuf, Mumtaz Din Wani and Tanzeela Bashir Qazi
Subject Area: 
Health Sciences
Abstract: 

Background: Colorectal cancer is a formidable health problem worldwide. It is the third most common cancer in men (10.6%) worldwide and second most common among females (9.4%) worldwide. Aim: The aim of the study is to investigate the role of faecal calprotectin in colorectal patients and to compare the sensitivity of faecal calprotectin and Faecal Occult Blood test among colorectal patients. Methods: It was a descriptive cross-sectional study that was conducted in the department of Surgery, Government Medical college Srinagar from August 2017 to August 2018. The study participants were histologically diagnosed cases of colorectal cancer. A total of 120 patients were included in analysis. Results: Mean ± S.D. for age was 59.38 ± 11.656. Majority of the participants (52.2%) were predominantly males. The site of lesion for most of the participants (68.3%) was colon followed by rectum (31.7%). A statistically significant association of faecal calprotectin was found among those having adenomatous polyp, ulcerative colitis and crohnsdisease. Conclusion: Due to the higher sensitivity of calprotectin for colorectal cancer or adenomatous polyps or Inflammatory bowel disease, it has the potential for a greater reduction in mortality caused by colorectal cancer.

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