The authors are commenting on the article entitled “Focal and diffuse chronic central serous chorioretinopathy treated with half-dose photodynamic therapy or subthreshold micropulse laser” published by van Rijssen et al. in Am J Ophthalmology. DOI: http/dx.doi.org/10.1016/j. ajo.2019.03.025. Published online: April 2, 2019. The authors concluded that half-dose photodynamic therapy is the preferred treatment over high-density subthreashold micropulse laser treatment for chronic central serous chorioretinopathy patients, both with focal and diffuse leakage on fluoresce in angiography. However, the validation, extrapolation, and generalizability of these outcomes can be made only after inclusion in the stepwise multivariate logistic regression analysis of all the missing data mentioned by us in addition to the baseline characteristics already assessed in this study.
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