
Guillain-Barre syndrome (GBS) is an acute polyradiculoneuropathy which is frequently severe in course and assumed autoimmune disease pathogenically. Infection is most common assumed trigger, either respiratory or gastrointestinal. Although rare, there are case reports published worldwide that pregnancy and postpartum period are high risk condition for GBS. It is associated and reported in all trimester. GBS worsen in postpartum periods and had a bad prognosis. Recurrence also been reported in subsequent pregnancies. Here we report a case of GBS in first trimester, post dilatation and curettage procedure done after spontaneous abortion. Early diagnosis with high index of suspicion with early and aggressive management can reduce morbidity and mortality in this group of patients.