
Background: Acute pancreatitis is a common disease having wide clinical variations. It may vary in severity from mild self-limiting pancreatic inflammation to pancreatic necrosis which is a life threatening condition causing to multi organ failure syndrome. Methodology: We conducted a retrospective study in Rama Medical College Hospital and Research Centre, Pilkhuwa, Hapur in the Department of surgery from April 2017 to April 2019.All the patients with the diagnosis of acute pancreatitis were included in this study. Results: The present study was done in the patients who were admitted in the surgery ward with the diagnosis of acute pancreatitis during April 2017 to 2019.Fifty nine patients of acute pancreatitis were there. Out of these female patients were more in number followed by male patients. The foremost cause of acute pancreatitis was gall stone diseases in female patients and alcoholism in male patients. The mean age was 45-55 years in both sexes. Most patients were managed conservatively in high dependency surgical intensive care unit. Severe acute pancreatitis had poor prognosis. Surgical outcome was also not good. Conclusion: Acute pancreatitis is more prevalent in female population followed by male. Gall stone pancreatitis was more common in females and alcohol abuse in males. Conservative management was more fruitful than surgical intervention.