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Moringa oleifera leaves extract acts as anti-cancer against breast cancer cell lines

Author: 
Ramanuj K Gupta, Dharmshila Kumari, Aniket K., and Ajit K Saxena
Subject Area: 
Life Sciences
Abstract: 

Medicinal plants are most important indigenous source of herbal medicine for developing country. There are few of medicinal plants were used for treatment of breast cancer have been documented. The present study aimed to assess the cytotoxic effect of Moringa oleifera plant leaf extracts on three different cell lines (MCF-7, MDA-MB-468 and MDA-MB 231). Different doses of plant extract and standard were taken and introduced into cancer cells lines were recorded at 72 hrs respectively it clearly showed an effective cell growth inhibition of human breast cancer cell lines MCF-7, MDA-MB-468 and MDA-MB-231 in a dose and specific time duration for the inhibition of cells. The present study demonstrates that M. oleifera leaf extract have anti-proliferative and pro-apoptotic effects on breast cancer cell lines in a concentration and time-dependent manner, which suggests their potential to be used as a new therapeutic strategy for breast cancers. These results highlight the novelty of this finding because earlier no report has yet been cited on the effectiveness of Moringa leave extracts found in the indigenous environment as an anti-cancer agent against breast. Our study is the first of its kind to evaluate the anti-malignant properties of Moringa leaves. These findings suggest the leaf extracts of Moringa collected from the widely distributed in different Indian region possess anti-cancer activity that can be used to develop new drugs for treatment of breast cancers.

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