Introduction: Childhood tuberculosis traditionally had a lower priority than adult tuberculosis (TB) within National Tuberculosis Programmes (NTP's), because it is largely non-infectious; cases have been thought to be few, and assumption that effective control of adult TB could prevent childhood TB. In many countries with high TB incidence, however; childhood TB (i.e. TB among population aged less than 15 years) constitutes a significant proportion (approximately 11-14%) of TB case load and under 5 mortality. However there is limited information of the basic demographic, clinical characteristics and programme defined outcomes of these children with TB. Present study is carried out at city tuberculosis center, solapur with purpose to find out treatment outcome in children with tuberculosis treated under short course chemotherapy. Aim and Objectives: To assess the outcome of intermittent short course chemotherapy in pediatric tuberculosis. To identify risk factors for non-compliance during intensive phase and continuation phase of DOTS. Material and Methods: A descriptive longitudinal study conducted on all paediatric (1-15 years) patients registered for tuberculosis treatment in city tuberculosis center solapur during 1st November 2010 to 31st December 2012. Results: Out of total 93 paediatric patients registered for treatment, 36.56% were between 1- 5 years of age. Male & female patients were distributed in almost equal proportion. Acid fast bacilli i.e. mycobacterium detected in 10.75% of patients. 84.95% patients were completed the DOTS treatment, while 3.22% were defaulter and outcome in 1.05% was treatment failure. Conclusion: Treatment completion rate in children with tuberculosis treated with DOTS is significantly high.