
This research is mainly focused on Solanum rugosum which is a well-known Solanaceae found in Côte d'Ivoire. The goal of the study was to investigate the chemical composition of the crude extract; total phenolic, flavonoid compounds, antioxidant and antibacterial activities of S. rugosumfrom Côte d’Ivoire. It was found that Ca, K, P, Cl, S, Si, Pb, Na, Fe, Al, Cu, Zn, Va, Se and Mg are the major minerals imbedded in the plant. The phytochemical screening using thin layer chromatography (TLC) carried out on the extracts of the leaves, stem bark and the roots bark has highlightedthe presence of various classes of secondary phytocompounds (coumarins, flavonoids, alkaloids, sterols, tannins and terpenes). The crude hydromethanolic extracts has shown a specific potential by reducing iron and trapping DPPH free radicalmainly in the leaves of S. rugosum. The extracts of the leaves showed a significant action against Staphylococcus aureus ATCC, Staphylococcus aureus 348C / 19 CNRa and Pseudomonas aeruginosa ATCC.