Non Hodgkin’s Lymphoma (NHL) testes is a rare disease that comprises nearly 1% of all cases of NHl and around 9 % of all cases of testicular tumor. We report here a rare case of 56 year old male who presented with complains of pain and swelling in left testes. USg shows para aortic lymphadenopathy with raise vasculature on colour Doppler. Tumor markers were raised. MRI brain shows finding of Lymphoma. PET CT shows raised SUV uptake in left testes . Multiple positive pelvic and paraaortic lymph nodes. Left inguinal orchidectomy was performed and histopathology shows tumor cells arranged in sheets and on immunohistochemistry , it was negative for CD20 and CD45 and positivr for CD 3. The patient was started on chemotherapy i.e CHOP ( Cyclophosphamide, Oncovorin, Adriamycin and Prednisolone). The role of rituximab is linked to CD-20 positive lymphomas only as Rituximab is a monoclonal antibody agent against CD 20. The overall prognosis of NHL testes is very poor.
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