A 40 year old female presented to the emergency department (ED) with complaints of loose motion, vomiting, spasmodic abdomen pain and rash all over the body after ingestion of 1 tablet of pantaprazole 40 mg, around two and half hours prior to arrival. In the ED, she was diagnosed with anaphylactic shock with gastrointestinal and skin involvement and hemodynamically instability. She was resuscitated with injections epinephrine, pheniramine, ranitidine, and hydrocortisone, along with intravenous fluid and oxygen, for management of anaphylactic shock. Thereafter, patient was shifted to the intensive care unit, and was discharged after uneventful 24 hour observation.
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