CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Salivary lactate dehydrogenase a diagnostic markers for oral Leukoplakia- a short study

Author: 
Dr. Manoj Upadhyay, Dr. Rahul Puri Goswami, Dr. Sakshi Malik, Dr. Ashish Vyas and Dr. Manish Sharma
Subject Area: 
Health Sciences
Abstract: 

Introduction: Leukoplakia has evolved as a clinic-pathologic concept over many years, with the current clinical term being established worldwide. Insightful of the biology of leukoplakia is the concept of cellular atypia and epithelial dysplasia. It is the most common potential premaliganant lesion and has high incidence of conversion into malignant lesion. Various noninvasive methods were studied to demonstrate metabolic changes in oral pathological condition. Lactate dehydrogenase (LDH) enzyme is found in various cells in our body. Salivary LDH is similar to that found in oral epithelium & serum. Conversion of a normal tissue into a premalignant lesion result in an alteration in glycolytic pathway causes variation in LDH level. Therefore this study was carried out to determine changes in salivary LDH level of individual with normal and to compare it with patient of different grades oral dysplasia. Method: Sixty patients reported to Department of Oral Medicine & Radiology at Vyas Dental College & Hospital were enrolled into study of which 15 patients with for each grade of dysplasia and 15 healthy controls were taken. Unstimulated saliva measuring 1ml was collected from each of the patient by spit method. The collected sample was centrifuged & evaluated for LDH level using Vitros 250 autoanalyzer. The data obtained were subjected to statistical analysis. Result: Salivary LDH level was higher in different grades of dysplasia patients when compared to healthy control group. Conclusion: Salivary LDH estimation can prove to be a valuable substitute as a biochemical marker as it is simple noninvasive and easily accepted by the patient.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran