Serum iron profile and hemoglobin level in chronic kidney disease

Background: In India, CKD one of the major public health problems with many complications. Its progression, can lead to haematological abnormalities including low hemoglobin levels .Increasing renal anemia can further lead to morbidity and mortality in the patients. Aims and objectives: To study serum iron profile and hemoglobin level in patients with CKD. Materials and Methods: 70 patients out of total 96 patients with CKD were studied in the Department of Medicine, BRD Medical College from September 2015 to August 2016. Hemoglobin, serum iron, serum ferritin levels, transferrin saturation, total iron binding capacity and creatinine level were assessed for all patients. Data was analyzed using IBM SPSS software. Results: Maximum cases were between 25-50 years (n=32, 45.7%) with male preponderance (n=22, 65.71%). Anemia was more common in male population (58.92). Out of 70 patients, 80%, 65.7%, 40%, 34.3% and 37.14% had low haemoglobin level, decreased MCV, decreased ferritin level, decreased iron level and increased TIBC respectively. Haemoglobin level was decreased in 56 patients, of that 35.71% and 5.35% had decreased and increased serum iron level. Out of 26 patients with decreased TIBC, 69.23% had decreased hemoglobin level. Of the 58 (82.85%) patients who were on iron supplementations, 41.37% had decreased ferritin levels. Out of 55 patients who had creatinine level between 5-15 mg/dl, 42 (76.36%) had anemia. Conclusion: Decreased hemoglobin level is one of the commonest manifestations in CKD patients with male preponderance.