CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

 

 

 

Toxicity effect of calcium carbide coerced ripened pawpaw on the liver mass of the wistar rats

Author: 
Ogoun, Timipa Richard and Dibagha, Izibeya James
Subject Area: 
Health Sciences
Abstract: 

The liver, which is one of the largest organs of the body with varying degree of functions is prone to diverse ailments. This study is aimed at evaluating the effect of Calcium Carbide coerced ripened Pawpaw on the Liver mass of the Wistar rats. Mature unripe Pawpaw’s were plucked off from the parent plant and were dividing into two groups; The first group was kept to rip at normal room temperature while the second group was induced with Calcium Carbide to rip. 10gram of Calcium carbide was placed in a bowl containing 5ml of water for dissolution in a closed metal bucket containing 1kg of the fruit (pawpaw) rapped with black nylon and was allowed for two days. After ripening, sampled fruits were washed and juiced. 600g of both the naturally ripened and calcium carbide ripened pawpaw were peeled separately and blended in an electric blender with 350ml/1L of deionized water. The juice was filtered and poured into clean bottles labeled (CaC2 induced ripened juice and naturally ripened pawpaw juice). A total of 21 adult Wister rats of both sexes weighing between 126.9- 214.3g were used. The Wistar rats were divided into three groups based on the body weight and then different concentrations of naturally ripened and calcium carbide induced ripened Pawpaw were administered orally. LD50 was carried out using Lorke, 1983 method. Group 1: Normal control group of 4 rats (2 males and 2 females) receive normal water and feeds only as placebo. Group 2 : Treatment Group (1) of 4 rats (2 males and 2 females). Group 3: Treatment Group (2) of 4 Wistar rats (2 males and 2 females) received Calcium Carbide ripened pawpaw for 4 weeks. 5ml/kg for both the natural fruit and the CaC2 ripened fruits were administered against each body weight of the adult Wistar rats. The Wistar rats were weighed and one Wistar rat was sacrificed weekly in groups. Blood and organ(liver) were collected from the three groups for histopathological analysis. The results showed Hepatocyte Hypertrophy, focal inflammation, Sinusoidal Dilation and amongst other. In conclusion, the consumption of fruits ripened with Calcium carbide pose detrimental effect on the liver, which could lower its functionality and integrity.

PDF file: 

Announcement

  • FAST PUBLICATION : November 2022
  • IMPACT FACTOR: 7.992
  • QUALIS INDEXING
  • HIGH IMPACT FACTOR
  • INTERNATIONAL JOURNAL OF CURRENT RESEARCH

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

EDITORIAL BOARD

Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran