Uterine prolapse is the leading cause of ill health that exists throughout the entire nation especially in rural regions. While studying the situation globally, World Health Organization estimates that the reproductive ill health accounts for 33% of the total disease burden in women globally. The main aim of the present study was to assess the Effectiveness of Structured teaching programme on Prevention of Uterine prolapse among Multiparous women residing in selected villages at Kirumambakkam Primary Health Centre, Puducherry. The study samples were 100 multiparous women selected from two different villages for experimental and control group. Comparing the pre-test & post-test scores of knowledge, attitude and practice between experimental and control group, the structured teaching programme on prevention of uterine prolapse provided by the investigator proved to be highly effective in the improvement of knowledge, attitude and practice among multiparous women in experimental group. The STP was effective and it is also suggested that the programme should be continued in order to uplift the overall health and practices of mothers. Hence, it will help to reduce the incidence of Uterine prolapse and enhance the quality of life in future.