Beneficial Effect Of Azadirachta Indica Leaf Extract On The Cardiovascular System In Different Animal Models

Neem (Azadirachta indica), an indigenous plant is reported to have antidiabetic, anti-inflammatory, antifungal and several other medicinal properties. More than 135 active principles have been isolated from different parts of Neem tree and several reviews have been published regarding their beneficial effect. In this experiment, anti arrhythmic action was observed within two minutes of NLE administration and this was persistent in nature. Present work demonstrates the various beneficial effects of low dose NLE like lowering of blood pressure and terminating cardiac tachyarrhythmia.Neem seed oil was obtained in pure form from Indian Herbs Research Supply Company Limited, Saharanpur, UP. The Ethical Committee approval was taken from the Institutional Ethics Committee of Veer Surendra Sai Medical College and Hospital, Burla, Odisha.