Clinical profile of thyroid disorders

Aims and Objectives: To study incidence, signs, symptoms, response to treatment & follow up of patients with thyroid disorders. Methods and Material: One hundred fifty patients of thyroid disorder are studied for signs, symptoms and investigations like thyroid function test, lipid profile, ECG, 2-D echo, USG neck. All patients are followed up after 2 months of treatment. Observations and Results: Thyroid disorders are common in females (80%). Ninty three patients (62%) are hypothyroid, 35 are hyperthyroid and 22 euthyroid patients having nodular disorder. Generalised weakness and lethargy is most common complaint in 51 (54.84%) and dry skin is most common finding in 46 (49.46%) hypothyroid patients. Tremulousness is most common complaint in 20(57.14%) and tremors is most common finding in 22(62.86%) hyperthyroid patients. Colloid goiter is most common ultrasound finding in 23 cases. There is statistically significant difference in level of TSH, FT-3 and FT-4 in hypothyroid and hyperthyroid patients after 2 months of treatment (p<0.01). and TSH suppression therapy. Conclusions: Thyroid disorders are very common in young and middle aged females. Hypothyroidism is treatable cause of weight gain, menstrual irregularities, infertility, pericardial effusion and dyslipidemias. High index of suspicion is required for thyroid disorders, in special population like young, middle aged females, pregnant females, patients with arrhythmias. Early Diagnosis, Prompt treatment, Regular follow up with thyroid function tests, accordingly change in treatment regimen and compliance to treatment have significant role in thyroid disorders and their prognosis.