Aim: To evaluate and compare the post operative complaints in diabetic and non diabetic complete denture wearers. Objective: The objective of the study was to evaluate and compare problems faced by diabetic and non diabetic complete denture wearers. Materials and Method: This study was done with a sample of 100 patients out of which half were diabetic and half were non-diabetic. A self-administered structured questionnaire pretested through a pilot survey was used in the study. The data was analyzed using the Graphpad Prism 7.0 version. Results: results show significant difference in almost all of the questions except appearance of white or reddish lesion, pain while eating, difficulty in speech, difficulty in chewing which were non significant between diabetic and non diabetic patients. Conclusion: Diabetic patients experienced more problems after wearing a complete denture as compared to non diabetic patients. The most frequent problem listed by 78 % of diabetic patient was bad smell.