Diarrhoea is a major public health problem in the developing countries of Latin America, Africa, Asia, and parts of the Middle East, included Thailand. Prevention and control are need required. Therefore, this cross-sectional study aimed to assess the knowledge, attitude, and practice (KAP) regarding diarrhoeal disease among rural villagers in Nonghuawaen village, Kham Thale So district, Nakhon Ratchasima Province, Thailand. The 113 samples were purposive selected included head or represent of household, during January and April 2015. A predesigned KAP questionnaire was utilized to collect the data from them included socio-demographic characteristics, KAP. The results revealed that most of the represents, they were 26-35 years old, female, primary school, and agriculture. The self-reported prevalence of diarrhea was 16.8% during the last year prior to the survey. 67.30% of represents had received information regarding diarrhoeal disease. Of 44.2% represents had a fair level of knowledge regarding diarrhoeal disease, causes of disease, sign and symptom, and prevention and control (xˉ=10.1, S.D.=6.24). Of represents, 75.2% had a moderate attitude regarding diarrhoeal prevention and control (xˉ=2.21, S.D.=0.45). Of represents, 61.9% had a good practice regarding diarrhoeal prevention and control (xˉ=2.61, S.D.=0.49). Chi-square testing indicated that gender (female; X2=1.02), age group (26-35 and 36-45 year old; X2=1.01), education (Senior high school; X2=1.24, High vocational certificate; X2=1.22) and occupation (Government officer; X2=1.31), were significantly associated with diarrhoeal disease (p-value<0.05). This finding shows a moderate knowledge, and fair attitude on diarrhoeal disease, therefore, health education is need required in this areas.
