Work productivity is an illustration of the ability of workers to produce output. The higher the output produced by a worker, shows the higher the level of productivity of these workers. Centro de Saúde (CdS) area of Servços Municipio Saúde (SMS) Municipio de Baucau is the most many absorb health workers in Municipio de Baucau. But many factors influence productivity the work of health workers at these government institutions. Therefore, what was analyzed in this study was work motivation factors, work discipline and work environment towards the work productivity of CdS health workers in the SMS area Municipio de Baucau. This study aims to analyze the influence of work motivation variables, work discipline, and work environment on the work productivity of CdS health workers in the area of SMS Municipio de Baucau. Data in this study using primary data through distributing questionnaires to 110 health worker respondents in the CdS SMS area Municipio de Baucau with a list of questions prepared. To reach the goal, in this study using a cross sectional survey method. The sampling technique uses the Slovin formula. Sampling was done using the Proportionate Random Sampling method. Data analysis in this study uses Analysis Multiple Linear Regression using SPSS version 22 software for Windows. The results of this study indicate that the variables of work motivation, work discipline, and work environment are an influential positive and significant effect on work productivity of health workers in the CdS area of SMS Municipio de Baucau, and has an effect of 57.0% and the remaining 43% is influenced by other variables.