Assessment of incidences of mycological infections in burn wounds and their Antimycotic resistance pattern at tertiary care hospital in Western Rajasthan, India

Fungal-infection in the burn patient is a leading cause of morbidity and mortality known to cause many deaths remains one of the most challenging concerns for the burn treating team. This study was conducted at the tertiary care level to determine frequency of wound infections by fungus in burn patients and antimycotic resistance pattern of isolates. One hundred & fifty patients of all age groups were included in the study. Samples were collected from the burn wounds & processed microbiologically. Fungi were found to cause burn wound infection in 40 out of 150 cases (26.67%) with predominant Candida non-albicans spp. 24 cases.-60%, Moulds 12 cases- 30% & C.albicans 4 cases- 10 % among total fungal isolates. 75% Moulds were resistant to fluconazole& itroconazole, while 100% were resistant to clotrimazole. 50% candida albicans were resistant to Fluconazole& Itraconazole while 75% were resistant to clotrimazole. Among Candida non- albicans 75% were resistant to fluconazole, Itraconazole & clotrimazole. Voriconazole is still responding well in 85-90% cases due to its broad spectrum & replaced as first line therapy. This study identified clinicoepidemiological profile of burn wound infections by fungus in Western Rajasthan & concluded that a proper care of burn wound that predispose to fungal invasion, early diagnosis & appropriate treatment may helps in reduction of infection rates & decrease in morbidity & mortality rate.