Background: Laryngeal cancer is a common disease a among Sudanese smoker. It is a type of neoplasm that has the largest male to female ratio in Sudan. Objective: To provide a review of the clinical pattern and to determine the etiology of laryngeal cancer among the Sudanese patients. Justification:- • Cases of laryngeal cancer are increasing in Sudan. • There were no publications regarding laryngeal cancer in Sudanese patients to my knowledge expect that reported by Sharfi. Methods: It was a prospective study, random sample, cross sectional where 82 patients who were treated at Khartoum state hospitals during the period from March 2014 to Nov 2016. Videolaryngoscopy, plain chest x-ray, CT - scan of the neck and thorax and Microlarynogoscopy studies were done to all patients. Results: The larynx was examined with Direct microlarynogoscopy for all patients. laryngeal masses were found in the vocal cords. Biopsies confirmed the diagnoses. Conclusion: Laryngeal cancer was common among Sudanese smoker patients and less common in non smokers.