Clinical study of usr-e-wazifi nazfur reham (dysfunctional uterine bleeding) and management with unani formulation

Background: Dysfunctional uterine bleeding (DUB) is a common debilitating problem amongst women in all age groups and accounts for 20% of gynaecology visits. The term ‘dysfunctional uterine bleeding’ was specifically used when menorrhagia was not associated with any genital tract abnormalities, general or endocrinological diseases. In this case, hormonal imbalance is considered the root cause of hyperplasia of the endometrium it results menorrhagia.1,2,3,4 Objectives: The aim of the study was to evaluate the efficacy of Unani formulations in the management of dysfunctional uterine bleeding. With an objective to evaluate the efficacy of unani drugs in the management of Dysfunctional Uterine Bleeding (Usr-e-Wazifi Nazf-ur-Reham). Methods: Standard controlled randomized single blind study was carried out at department of Amraz-e-Niswanwa Qabalat, Karol Bagh, New Delhi by registering 80 clinically diagnosed cases of DUB were enrolled in both test group (40 patients) and control group (40 patients) after getting their consent to participate in the study. Treatment was given for every 15 days or as per assessment of the patient for 90 days and evaluation of treatment was done by the assessment of menstrual blood loss (MBL) using the Pictorial Bleeding Assessment Chart before and after the treatment, relief of the associated symptoms and regularity of menstrualcycles. Subjective and objective parameter were assessed by Z-test. Results: There was a significant reduction of menstrual blood loss (MBL) in both test group and control group (P < 0.01). The irregularity of menstrual cycles was rectified and menstrual cycles were regular with duration of 25-30 days. Of the 40 patients in the test group, 29 (72.5%) were cured, 9 (22.5%) were relieved, and 2 (5%) were partially relieved. Conclusion: The Unani drugs in the test group were found to be effective as they are having haemostatic, styptic, analgesic, and anti-inflammatory, anti-spasmodic, blood purifier and uterine tonic properties. The formulation is rich in oxides of iron, tannin, and phosphorus, hence found to be beneficial in replenishing the lost minerals in excessive menstrual flow.