Aim: This study aimed to evaluate the effectiveness of four commercial desensitizing toothpastes in dentine tubule occlusion using the scanning electron microscopic analysis. Materials and Methods: The samples were divided into five groups having ten teeth each (n = 10); the groups were divided accordingly, Each of the five groups (A-E) were treated as follows Group A- Sensodyne Rapid (Strontium acetate), Group B – Sensodyne Repair (Stannous fluoride), Group C – BioRepair (Zinc-carbonate hydroxyapatite), Group D – Colgate Total Sensitive (New silica ), Group E- saline (control).Each tooth was then split longitudinally and was prepared for examination by scanning electron microscope under ×1000. Statistical Analysis: The scores were compared statistically within the groups using Mann Whitney test with a level of significance set at P<0.01. Results: Zn-CHA based toothpaste exhibited significant occlusion of dentinal tubules when compared to other groups Conclusion: The maximum desensitising efficacy was shown by Bio Repair (Zinc-carbonate hydroxyapatite) followed by Colgate Total Sensitive (New silica ) toothpaste.
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