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Differences of onset and duration of action in local anesthesia with the tumescent technique using lidocaine and epinephrine with a 1:500,000, 1:1,000,000 dilutionand control

Author: 
Aditya Husni, Frank Bietra Buchari and Utama Abdi Tarigan
Subject Area: 
Health Sciences
Abstract: 

Background: Many procedures today can be performed using the Tumescent local anesthetic technique. Several studies using this technique resulted in a clean, safe, and effective operating field, and can reduce the cost of several elective operations. Therefore, the researchers wished to investigate differences in duration and onset of action of Tumescent anesthetics during surgery and before surgery in different dilution concentration groups. Methods: This experimental analytical study was conducted to compare the onset and duration of local anesthetic action with the Tumescent technique using lidocaine and epinephrine with dilutions of 1:500,000, 1: 1,000,000 and controls usinglidocaine only. The subjects of this study were male or female young adults who met the inclusion criteria and exclusion criteria with the research formula obtained 10 samples in each group. Tumescent technique local anesthetic injection was performed in the hand area. Onset and duration were assessed by sensory sensation using the cotton wool test. Results: Based on ANOVA statistical test on the onset of action, there was no significant difference in the mean of onset in the three groups (p<0,945) and found a significant difference in the duration of work of the three groups (p<0,00). Conclusion: There was a significant difference in the duration of work between lidocaine-only group and dilution concentration groups (p<0,00).

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