Each person on the planet can be, distinguished at molecular level on the basis of high level of polymorphism in the succession of his or her DNA, which he or she acquires from his or her biological parents and is identical in each cell of the body. DNA fingerprinting, as this system of recognizable proof is called, can affirm with sureness the parentage of a person. The utilization of DNA profiling in the criminal equity framework is a vital issue in criminal specialists today. The innovation is changing quickly and a few new procedures are getting to be distinctly accessible. DNA profiling has been depicted as an effective achievement in criminological science. The forensic use of DNA profiling is a noteworthy commitment to an innovation which can help not just in including the offender additionally to avoid the innocent. In this article an endeavor is made to expound the changing situation of the innovation in the late years and in addition to introduce the some genuine situations where distinctive variations of the DNA fingerprinting innovation were effectively connected in understanding the criminal cases in the research centers.