This research presents the results obtained with students from BIOTERRA University in Bucharest and with pupils from “Ion Luca Caragiale” National College in Bucharest, with whom the university is in partnership, by applying of Electronic-learning (E-learning) and of Virtual Reality (VR) with aid of Information and Communication Technologies (ICT) in Biology. Such, has been applied the Computer-Assisted Instruction (CAI) through the “High School Educational Assistance” (HSEA) software application, by means of software educational presentations such as PowerPoint slides, Display Video Disc (DVD), demonstrated with the help of computer, of projector, smart board. Also has been applied the Internet, through YouTube videos, chat rooms, discussion forums on professional sites, Video Conferencing. In E-learning through VR in biological sciences a techno centric model based on technique and equipment was experienced, alongside with a computer-focused strategy and various methodologies made up by combining a variety of teaching methods such as CAI, demonstration, simulation, experiment, observation, modeling, working with electronic school book, electronic Interactive System of Noting for Efficiency of Reading and Thinking (ISNERT), computer discussions and debates. This research on E-learning and VR in Biology contribute to this area by numerous examples of biological learning units, lessons and courses based on them, but also by the functions, advantages, disadvantages, limitations of E-learning and Virtual Reality, as well as by ways to counteract these limitations identified in Biology. The E-learning and Virtual Reality bring a cognitive and affective plus, contribute to sustainable education, demonstrated by the results of the tests.
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