CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Endoscopic trans-sphenoidal approach for pituitary surgery: Retrospective and prospective study of 70 patients

Author: 
Nikunj R. Godhani, Harshil C. Shah, Jaimin K. Shah, Ankur B. Pachani and Vikash Singh
Subject Area: 
Health Sciences
Abstract: 

Background: Endoscopic trans sphenoidal approach is increasingly used in the treatment of pituitary adenoma. It is considered approach of choice in pituitary tumor surgery. There are varying opinions about results of endoscopic approach in pituitary surgery. We therefore Retrospectively & prospectively studied the outcome of endoscopic Approach in Pituitary surgery. Aim: To investigate the outcome of endoscopic Trans sphenoidal approach in patients with pituitary adenoma surgery. Methods and Materials: A prospective study of 70 patients undergoing endoscopic Trans sphenoidal excision in our institution from July 2013 to December 2015 was carried out. Diagnosis of pituitary adenoma was done by preoperative computed tomographic scan and magnetic resonace imaging, visual field charting, hormone profile. The results of Pituitary surgery were determined by assessing clinical signs of visual acuity, post op Hormone profile, Visual field charting as well as by MRI / CT scans. Results such as extent of excision, rate of relapse in functioning adenoma, visual improvement, incidence of DI were compared with other studies done in past. Results: Most common age group to be affected by pituitary tumors falls between 41-50 years of age.It is more common in Female 52% compared to Male 48%. Most common clinical symptoms in our series are Headaches followed by Visual disturbance. These symptoms of mass effect are much common than endocrinologic dysfunction of acromegaly and galactorrhea amenorrhea syndrome. Optic nerve involvement is other common clinical finding presenting in form of decreased vision or loss of vision, field defect or fundus changes. Commonest field defect is bitemporal hemianopia. Approximately half of the patients exhibited normal preoperative pituitary function in form of baseline hormone profile. Among 70 patients 37 were NFPA, 18 were GH adenoma, 2 were ACTH adenoma, 11 were prolactinoma and 2 patients with apoplexy. MRI is the diagnostic investigation of choice in pituitary tumors to define extent, invasion and relationship to major vessels and nerves. Total/near total removal was done in 63 patients and subtotal removal done in 7 patients. Adjuvant therapies were given in 8 patients. Two patients were given radiotherapy and 3 were given pharmacotherapy. The post operative complications were CSF leak 6%, Diabetes insipidus 21%. 59 patients had improvement in their symptoms including relief from headache, improvement in vision and endocrinal dysfunction. Post operatively visual functions improved in 35 patients and it remained stationary in 34 patients. Only one patient complained of worsening of his visual function and it was improved in follow up period. Conclusion: The Pituitary constitutes a unique class of intracranial neoplasia. widespread use of MRI is now accepted as imaging procedure of choice in the evaluation of these tumors. Trans-Sphenoidal surgery is the primary treatment of choice for this class of tumors. Which can achieve superior extent of resection with acceptable rate of complication. Though long term follow up is needed for better understanding of the result.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran