Extraction, formulation, phytochemical characterization, toxicity study and evaluation of analgesic activity of herbal spagyric essence (electrohomeopathic medicine) white electricity

Objective: This particular research emphasis on the formulation, characterization and in vivo evaluation of analgesic activity of herbal spagyric essence (Electrohomeopathic medicine) White Electricity (WE) in Wistar rats. No scientific report has been available until date of WE. Therefore the current analysis focuses to prove scientific study of herbal spagiryc essence of WE. Materials and Methods: The Electrohomeopathic medicine WE is formulated by extracting and blending of spagiryc essence of specified herbal plants. The phytochemical characterization is done with help of qualitative chemical tests. The acute toxicity study is done with referring OECD toxicity guideline 420. The Analgesic activity of Electrohomeopathic medicine WE was carried out by the Acetic acid writhing reflex method, Tail immersion method and Hot plate method with using albino rats of either sex. The percentage protection against abdominal writhing and the pain reaction time were used to assess the degree of analgesia which has been measured and compared to control groups. Results: It was found that the Electrohomeopathic medicine WE is safe and non toxic. The acute toxicity study confirms the safety of drugs. It exhibited an excellent analgesic activity. The phytochemical investigation confirms the presence of phytoconstituents which justify the above pharmacological activity of WE.A decreasing the percentage abdominal writhing and increased the pain reaction time period when compared to control groups confirmed the potent activity of WE. Conclusion: This research indicates that electrohomeopathic medicine WE are relatively safe and effective in reducing pains in different animal models. Thus WE possess significant analgesic properties.