Human papillomavirus infection is the most common sexually transmitted viral infection. Over 120 types of HPV have been identified till date. Some of them cause wart like lesions of the skin, genital and oral mucosa and some are etiologically associated with cervical and anogenital cancer. Recent epidemiological studies are also suggestive of their association with oropharyngeal cancer. In this paper the prevalence and clinical aspect of HPV infections of the oral mucosa are briefly reviewed for the purpose of updating the oral health professionals and raising the awareness of emerging relationships being established between HPVs and some oral diseases including oral cancer, thereby making it easier for dental practitioners to detect all the lesions of oral mucosa caused by HPV.
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