Objective: Post total knee replacement patients experience severe pain, anxiousness & discomfort which interfere with the patients’ functional mobility leading to slower recovery &increased pharmacological requirements. This study aims to find the effect of unconventional techniques, namely music on pain and anxiety in post-operative total knee arthroplasty patients. Design: Randomized control trial Methods & Findings: 54 subjects who underwent total knee arthroplasty were selected and randomly assigned into experimental and control group with 27 subjects in each through simple random sampling technique. The study was performed on post-operative day 1 or 2. A pre assessment of pain using VAS, anxiety & physiological parameters i.e. heart rate, respiratory rate, blood pressure & oxygen saturation was done in both the groups, following which both the groups received their scheduled exercise session, thereafter which the experimental group received 10 minutes of music in contrast to the control group who received 10 minutes of rest & a post intervention assessment was done. Results showed that even though there were some positive changes within the experimental group, there was no significant difference in pain (p=0.273), anxiety (0.498), or physiological parameters between the two groups. Conclusion: Music is clinically significant in reducing pain and anxiety post- Operatively there is no statistical difference in the results between the two groups.