Several studies have been undertaken thus far which compares the techniques of Inferior alveolar nerve block and Gow Gates mandibular block but a final conclusion on their efficacy is still controversial. This study, having been performed with standardized, accurate criteria, compared both the techniques between different age groups of patients. Thirty patients of age group 15-65 years were divided into group A (15 members) for Gow Gates technique and group B (15 members) for Inferior alveolar nerve block technique. Results were evaluated based on neurosensory testing once every 5, 10 and 15 minutes after anesthetising the tooth. In conclusion, experienced surgical skills are required for the success of the classical Gow-Gates technique. Inferior alveolar nerve block showed promising results in this study.