In this work, the piezoelectric response of modified asphalt design that can significantly solve damage that arises from overloading and high traffic load effects during the service-life were studied. The piezoelectric response of standard and modified binder with 0%, 5%, 10% and 15% of kaolin and hydrated lime content have been studied using voltmeter and Marshall compressive test machine. The results showed that the addition of kaolin and hydrated lime induces the piezoelectric response compared to the standard asphalt mixture. Various types of loadings have been considered throughout this study. It was determined that the type of modifier and applied load have an effect on the result of piezoelectric response on the surface and within an asphalt pavement structure. Also the result showed that modification of bitumen by kaolin and hydrated lime enhances its performance characteristics as well as significantly alters its rheological properties. The rheological studies on kaolin and hydrated lime modified bitumen were made through penetration test. It was observed that kaolin and hydrated lime showed an effect on penetration. Better results were obtained when hydrated lime concentration was at 15%. The mechanical properties of the standard asphalt mixture and modified asphalt mixture with kaolin and hydrated lime were evaluated using Marshall immersion test. This study showed that the effect of kaolin and hydrated lime modifiers with 5%,10% and 15% of modifier satisfy the minimum Ethiopia road authority acceptance criteria of air voids(except at 5%,10% hydrated lime and kaolin content respectively), void mineral aggregate, void filled with asphalt and Marshall stability butflow value do not meet Ethiopia RoadAuthority acceptance criteria.