Pumsavana Krama is one of important concept mentioned in ancient Ayurveda. It is preferably used to achieve the desirable child. Some of the theories postulated to determined the sex of embryo by our Ayurvedic Acharyas under the heading of Pumsavana Karma and general public is curious to know mystery of this concept. To determine sex of future offspring is an offence now a days because of many factors. The scientific review of this concept with modern embryology is felt. Study of modern embryological development process of urogenital system regarding the determination of sex is considerable to prove the efficacy and mode of action of Pumsavana Karma and the Drugs related. Drugs used for Pumsavana Karma are directly or indirectly acts on the pituitary gland and stimulates the secretion of hormones are responsible for the particular gonadal and sex organs development in male or female baby. For desirable results one should follow the methodology of Pumsavana karma as explained by Acharyas to see its mystery. How the drugs used during the procedure helps in the development of internal & external male and female urogenital system is discussed and conclusion is required further study.
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