High-temperature cooked meat contains NOCs, heterocyclic amines and polycyclic aromatic hydrocarbons. In rodents, a high intake of such compounds induces prostate tumours. In this article the association between heterocyclic amines, a common meat mutagen and prostate cancer is studied. The normal cells from the prostate gland are extracted and are treated with the above mentioned mutagens to study the cell viability, proliferation and the effects of the mutagens on the chromosomes. The cells showing increased proliferation rate and showing some chromosomal aberration in the metaphase plate indicates its conversion from normal to cancerous cells. The rate of conversion of normal cells to cancerous cells by a specific mutagen determines its mutagen city.
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